What is the Impact of Mitochondrial DNA Mutations?
Mutations in mtDNA can impact cellular function in several ways:
Disrupting the electron transport chain and ATP production. Increasing the production of ROS, leading to further cellular damage. Impairing the synthesis of proteins necessary for mitochondrial function.
These disruptions can lead to a variety of mitochondrial diseases, which often affect tissues with high energy demands such as muscle and nerve tissues.
