The development of various staining techniques was a game-changer for histology. Hematoxylin and eosin (H&E) staining, introduced in the late 19th century, remains a cornerstone of tissue examination. These techniques allow for the differentiation of cellular components, making it easier to identify and study various tissue types and cellular structures. The introduction of immunohistochemistry later provided even more specificity, enabling the visualization of specific proteins within cells and tissues.
