Thiamine deficiency is implicated in the pathogenesis of multiple diseases. For example, [beriberi](href) is a classic disease caused by thiamine deficiency, presenting with symptoms ranging from cardiovascular issues (wet beriberi) to peripheral neuropathy (dry beriberi). In chronic alcoholics, thiamine deficiency is often linked to Wernicke-Korsakoff syndrome, a severe neurological disorder. Histologically, these conditions exhibit specific tissue alterations that can be identified and linked to thiamine deficiency.
