The main function of ankyrin B is to facilitate the attachment of membrane proteins to the cytoskeleton. This attachment is essential for maintaining cell shape, polarity, and the proper functioning of cellular signaling pathways. In neurons, ankyrin B helps to localize sodium channels, thereby influencing action potential propagation. In cardiomyocytes, it ensures the proper functioning of cardiac ion channels and transporters, which is crucial for cardiac excitability and contractility.
