What is the Clinical Significance of Stromal Tissue?
Stromal tissue has significant clinical implications:
Cancer: The tumor microenvironment includes stromal cells that can influence tumor growth, metastasis, and response to therapy. Fibrosis: Excessive deposition of ECM components by fibroblasts can lead to fibrotic diseases affecting organs like the liver, lungs, and kidneys. Wound Healing: Stromal cells play a key role in tissue repair and regeneration, making them targets for therapeutic interventions in chronic wounds and injuries. Inflammatory Diseases: The stroma's immune components are involved in conditions such as rheumatoid arthritis and inflammatory bowel disease.
