What is the Clinical Significance of Speckled Patterns?
In clinical histology, speckled patterns can have diagnostic value, especially in the context of autoimmune diseases. For instance, the presence of a speckled pattern in antinuclear antibody (ANA) testing is commonly associated with conditions like systemic lupus erythematosus (SLE) and Sjögren's syndrome. The pattern can provide insights into the type of antibodies present and help guide further diagnostic testing.