The expression of CD1a can have significant clinical implications. For example, Langerhans cell histiocytosis (LCH) is a rare disorder characterized by the proliferation of CD1a-positive Langerhans cells. Diagnosing LCH often involves detecting CD1a in tissue biopsies. Additionally, alterations in CD1a expression have been observed in certain inflammatory and autoimmune conditions, making it a potential biomarker for these diseases.
