What is the Clinical Significance of Alpha Secretase?
Given its role in preventing amyloid-beta formation, alpha secretase is a potential therapeutic target for Alzheimer's disease. Enhancing alpha secretase activity could reduce amyloid-beta levels and mitigate disease progression. Additionally, alpha secretase is involved in the shedding of several cell adhesion molecules and growth factor receptors, making it relevant in other pathologies such as cancer and cardiovascular diseases.
