The basal ganglia are implicated in several neurological disorders: - Parkinson’s Disease: Characterized by the degeneration of dopaminergic neurons in the substantia nigra, leading to motor symptoms such as tremors, rigidity, and bradykinesia. - Huntington’s Disease: Involves the degeneration of neurons in the caudate nucleus and putamen, leading to uncontrolled movements and cognitive decline. - Tourette Syndrome: Associated with dysfunction in the basal ganglia circuitry, leading to repetitive motor and vocal tics.
