Mast cells are involved in a variety of clinical conditions. Their role in allergic reactions makes them a target for therapies aimed at treating allergies and asthma. In addition, mast cells have been implicated in chronic inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. Understanding the behavior and regulation of mast cells can therefore provide insights into the treatment of these conditions. Furthermore, mast cell disorders, such as mastocytosis, are characterized by an abnormal increase in mast cell numbers and can lead to a range of symptoms and complications.
