What is Super-Resolution Microscopy and How Does it Benefit Histology?
Super-resolution microscopy techniques, such as STED (Stimulated Emission Depletion), PALM (Photoactivated Localization Microscopy), and STORM (Stochastic Optical Reconstruction Microscopy), can surpass the traditional diffraction limit of light microscopy. These methods allow for resolutions down to 20-30 nanometers, enabling the study of molecular details within cells. However, they often require specialized equipment and complex sample preparation.