How is the Ubiquitin Proteasome Pathway Related to Histology?
In the context of histology, the UPP is crucial for maintaining cellular and tissue integrity. By eliminating damaged or misfolded proteins, the pathway ensures that cells function correctly and tissues remain healthy. Histological analysis often reveals the consequences of UPP dysfunction, such as the accumulation of protein aggregates in neurodegenerative diseases or the uncontrolled proliferation of cells in cancer.