SIRT1, short for Sirtuin 1, is a protein that belongs to the sirtuin family of proteins. These proteins are conserved across species and are involved in a range of cellular processes including aging, transcription, and inflammation. SIRT1 is a NAD+-dependent deacetylase, meaning it removes acetyl groups from proteins in a manner dependent on the presence of nicotinamide adenine dinucleotide (NAD+).