What is Senescence Associated Beta Galactosidase (SA β-gal)?
Senescence Associated Beta Galactosidase (SA β-gal) is an enzyme that is widely used as a biomarker to detect cellular senescence. It is an isoform of β-galactosidase that becomes active at a suboptimal pH (pH 6.0) in senescent cells. This enzyme hydrolyzes β-galactosides into monosaccharides, and its activity is often measured through histochemical staining.
