What is non-alcoholic fatty liver disease (NAFLD) and its histological features?
NAFLD is characterized by the accumulation of fat in hepatocytes in the absence of significant alcohol consumption. Histologically, it ranges from simple steatosis (fat accumulation) to non-alcoholic steatohepatitis (NASH), which includes inflammation and fibrosis. NASH can progress to cirrhosis and increases the risk of liver cancer.