MASP-2 (Mannose-binding lectin-associated serine protease 2) is a crucial enzyme in the lectin pathway of the complement system. The complement system is part of the innate immune response, which helps in the defense against pathogens. MASP-2 is specifically involved in the activation of the complement cascade when mannose-binding lectin (MBL) or ficolins recognize carbohydrate patterns on the surface of pathogens.
