Hamartin is a protein encoded by the TSC1 gene located on chromosome 9. It is best known for its role in the pathogenesis of Tuberous Sclerosis Complex (TSC), a genetic disorder characterized by the growth of benign tumors in various organs. Hamartin forms a complex with another protein called tuberin, encoded by the TSC2 gene, and together they play crucial roles in cellular growth and proliferation.
