gp130, also known as Glycoprotein 130, is a transmembrane protein that plays a vital role in cellular signaling. It is a common signal transducer for a variety of cytokines, particularly those in the interleukin-6 (IL-6) family, such as IL-6, IL-11, leukemia inhibitory factor (LIF), and oncostatin M (OSM). These cytokines are essential for regulating immune responses, hematopoiesis, and inflammation.
