GAD65, or Glutamate Decarboxylase 65, is an enzyme that plays a critical role in the synthesis of the neurotransmitter GABA. This enzyme is one of the two isoforms of glutamate decarboxylase, the other being GAD67. GAD65 is predominantly found in the central nervous system (CNS) and is involved in converting glutamate to GABA, which is an inhibitory neurotransmitter.
