Epidermolysis Bullosa Simplex (EBS) is a genetic disorder characterized by the formation of blisters within the epidermis, particularly in response to minor mechanical trauma. It is one of the major subtypes of Epidermolysis Bullosa (EB), a group of disorders that affect the skin and mucous membranes. EBS is primarily caused by mutations in the genes that encode for keratin proteins, which play a crucial role in maintaining the structural integrity of the skin.
