What is Allele Specific Oligonucleotide (ASO) Hybridization?
Allele Specific Oligonucleotide (ASO) hybridization is a molecular technique used to detect specific DNA sequences or genetic mutations. It employs short, synthetic oligonucleotides that are complementary to the target allele of interest. These oligonucleotides can distinguish between normal and mutated sequences, making ASO hybridization a powerful tool for genotyping and diagnosing genetic disorders.
