What Histological Features are Observed in Stage IV?
In Stage IV cancer, histological examination reveals several key features: - Anaplasia: Cells exhibit a loss of differentiation and appear abnormal. - Increased Mitotic Activity: A higher number of cells undergoing mitosis, indicating rapid cell division. - Invasion: Cancer cells infiltrate surrounding tissues. - Metastasis: Presence of cancer cells in distant organs, confirming the spread from the primary site.