mtor

Can mTOR Inhibition be Therapeutic?

Yes, mTOR inhibition has therapeutic potential. Rapamycin and its analogs, known as rapalogs, are used in cancer therapy due to their ability to inhibit mTORC1, thereby reducing cell proliferation and inducing autophagy. In transplantation medicine, rapamycin is used as an immunosuppressant. However, the complexity of mTOR signaling requires careful consideration of the potential side effects and the development of more specific inhibitors for therapeutic use.

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