What Histological Changes Occur in Atherosclerosis?
Atherosclerosis is characterized by the accumulation of lipids, cholesterol, and cellular debris within the arterial walls, forming plaques. Histologically, these plaques consist of a lipid core surrounded by a fibrous cap. Over time, they can lead to the thickening and hardening of arteries. The presence of foam cells, which are lipid-laden macrophages, is a key histological marker of atherosclerosis.