How Do Histological Changes in Myocardial Infarction Present?

During a myocardial infarction or heart attack, the histological examination reveals necrosis or death of cardiac muscle cells, also known as cardiomyocytes. This necrosis is typically followed by infiltration of inflammatory cells, such as neutrophils, and later by macrophages. Over time, fibroblasts replace the lost myocardial tissue with fibrous scar tissue, altering the heart's structure and function.