What Histological Changes Occur During Traumatic Injury?
Upon traumatic injury, several histological changes take place, including:
Cellular damage: Cells may undergo necrosis or apoptosis due to physical disruption of cell membranes. Inflammatory response: The injury site often exhibits an influx of inflammatory cells like neutrophils and macrophages, leading to swelling and redness. Extracellular matrix disruption: Collagen fibers and other matrix components are often damaged, affecting tissue integrity. Vascular changes: Blood vessels may rupture, leading to hemorrhage and subsequent clot formation.