What Histological Changes Occur During Pathogen Attack?
During a pathogen attack, several histological changes can be observed in the affected tissues. These include:
- Inflammation: Characterized by the accumulation of immune cells such as neutrophils and macrophages, and the release of cytokines and chemokines. - Cellular Degeneration: Pathogens can cause cell lysis, apoptosis, or necrosis, leading to tissue damage. - Granuloma Formation: In chronic infections, immune cells may form granulomas to wall off the pathogens. - Fibrosis: Persistent infections can lead to the deposition of fibrous tissue and scarring.
