What Histological Changes Occur During Epidermal Disruption?
The histological changes depend on the type and severity of the disruption:
- Inflammation: Inflammatory cells such as neutrophils and macrophages infiltrate the affected area. - Cellular Damage: Necrosis or apoptosis of keratinocytes. - Structural Changes: Breakdown of the extracellular matrix and loss of cellular cohesion. - Regeneration: Activation of the stratum basale to produce new cells.
