What Histological Changes are Observed in Diseased Glomeruli?
Histological examination of diseased glomeruli can reveal various structural abnormalities. In diabetic nephropathy, there is thickening of the basement membrane and expansion of the mesangial matrix. In glomerulonephritis, inflammatory cell infiltration and immune complex deposition can be observed. In cases of focal segmental glomerulosclerosis (FSGS), there is segmental scarring of the glomeruli.
