What Happens When Electrochemical Gradients Are Disrupted?
Disruption of electrochemical gradients can lead to various pathological conditions. For example:
Hypokalemia (low potassium levels) can cause muscle weakness and cardiac arrhythmias. Hyperkalemia (high potassium levels) can lead to dangerous heart dysfunctions. Cystic fibrosis results from mutations affecting chloride ion channels, disrupting ion gradients and leading to thick mucus production. Neurodegenerative diseases often involve disrupted ion homeostasis and membrane potential regulation.