The presence of eosinophilic bodies often indicates cellular injury, stress, or apoptosis. For example:
Mallory bodies in liver cells can indicate alcoholic liver disease or other liver pathologies. Councilman bodies suggest hepatocyte apoptosis, often due to viral hepatitis or yellow fever. Lewy bodies are diagnostic of neurodegenerative diseases such as Parkinson’s disease and dementia with Lewy bodies. Russell bodies may indicate chronic inflammation or plasma cell disorders like multiple myeloma.