What Contributes to Lower Sensitivity and Specificity?
Several factors can contribute to lower sensitivity and specificity in histological tests. These include:
1. Sample Quality: Poorly preserved or inadequate tissue samples can lead to inaccurate results. 2. Technical Errors: Mistakes during sample processing, staining, or interpretation can affect test outcomes. 3. Test Limitations: Some tests inherently have lower sensitivity or specificity due to the nature of the disease or the testing method. 4. Biological Variability: Differences in disease presentation among patients can also impact test performance.
