lower sensitivity and specificity

What Are the Alternatives When Sensitivity and Specificity Are Low?

When a test shows low sensitivity and specificity, alternative diagnostic methods may be employed. These include:
1. Molecular Diagnostics: Techniques like PCR and next-generation sequencing can offer higher accuracy.
2. Imaging Studies: Combining histological tests with imaging techniques such as MRI or CT scans can provide a more comprehensive diagnosis.
3. Combined Testing: Using a combination of several tests can improve overall diagnostic accuracy, compensating for the limitations of individual tests.

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