The JGA consists of three main components: 1. Macula Densa: A group of specialized epithelial cells located in the distal convoluted tubule that detect sodium chloride concentration in the filtrate. 2. Juxtaglomerular Cells: Modified smooth muscle cells in the wall of the afferent arteriole that synthesize, store, and secrete renin. 3. Extraglomerular Mesangial Cells: Also known as lacis cells, these cells are located outside the glomerulus and are thought to play a supportive role in the function of the JGA.
