What changes occur in the tissues during gastrointestinal diseases?
Histological examination can reveal various pathological changes in the GI tract tissues:
- Gastritis: Inflammation of the stomach mucosa, often showing infiltration of inflammatory cells. - Celiac disease: Characterized by villous atrophy, crypt hyperplasia, and increased intraepithelial lymphocytes in the small intestine. - Ulcerative colitis: Inflammation and ulceration of the colon mucosa, with crypt abscesses and loss of goblet cells. - Crohn's disease: Transmural inflammation, granulomas, and fissuring ulcers affecting any part of the GI tract.
