LELs are typically associated with chronic inflammatory conditions, particularly [autoimmune diseases](http://) such as Sjögren's syndrome and Hashimoto's thyroiditis. They can also be indicative of [malignancies](http://) such as [MALT lymphoma](http://) (mucosa-associated lymphoid tissue lymphoma). The exact pathogenesis involves a complex interplay between immune cells and epithelial cells, often driven by chronic inflammation and autoimmunity.
