Several factors can contribute to limited bioactivity in biological tissues and materials:
Material Composition: Materials with poor surface properties, such as low wettability or inappropriate chemical composition, can limit bioactivity. Surface Topography: Surface roughness and patterning can affect cellular adhesion and growth. Chemical Functionalization: Lack of functional groups on the surface can hinder protein adsorption and cell attachment. Sterilization Techniques: Some sterilization methods can alter the material surface, impacting its bioactivity.
