Several factors can cause extravasation, including:
1. Trauma: Physical injury to blood vessels can lead to rupture and leakage of blood. 2. Inflammation: Inflammatory processes can increase vascular permeability, causing blood components to leak into tissues. 3. Vascular Disorders: Conditions like hypertension, atherosclerosis, and [vasculitis]() can compromise the integrity of blood vessels. 4. Neoplasms: Tumors can erode or compress blood vessels, resulting in extravasation.