There are several isoforms of lysyl hydroxylase, including Lysyl Hydroxylase 1 (LH1), Lysyl Hydroxylase 2 (LH2), and Lysyl Hydroxylase 3 (LH3). Each isoform has distinct but overlapping substrate specificities and tissue distributions. For instance, LH1 is predominantly involved in the hydroxylation of collagen type I, while LH2 is important for collagen type IV.
