There are several types of CAMs, each playing a distinct role in cell adhesion:
Cadherins - Mediate calcium-dependent cell-cell adhesion. They are crucial in maintaining the structure of epithelial tissues. Integrins - Facilitate cell-ECM adhesion and signal transduction, influencing cell shape, motility, and cycle. Selectins - Involved in leukocyte-endothelial cell interactions, playing a role in the immune response. Immunoglobulin superfamily CAMs (IgSF CAMs) - Participate in both cell-cell and cell-ECM adhesion, impacting immune responses and neural connections.
