What are the therapeutic potentials of targeting LH2?
Given its role in collagen modification and fibrosis, LH2 is a potential therapeutic target for treating fibrotic diseases and connective tissue disorders. Inhibitors of LH2 are being explored for their ability to prevent excessive collagen deposition in fibrotic tissues. Additionally, gene therapy approaches aim to correct PLOD2 mutations in patients with congenital disorders like Bruck syndrome.
