What are the Techniques to Study Tissue Heterogeneity?

Several techniques are used to study tissue heterogeneity:
- Histological Staining: Staining methods, such as H&E staining and immunohistochemistry, highlight different cell types and structures within tissues.
- Microscopy: Various microscopy techniques, including light microscopy, electron microscopy, and confocal microscopy, provide detailed images of tissues at different scales.
- Molecular Profiling: Techniques like single-cell RNA sequencing and proteomics allow for the analysis of gene and protein expression at the single-cell level, revealing the molecular heterogeneity within tissues.