What are the Techniques to Study Tissue Heterogeneity?
Several techniques are used to study tissue heterogeneity: - Histological Staining: Staining methods, such as H&E staining and immunohistochemistry, highlight different cell types and structures within tissues. - Microscopy: Various microscopy techniques, including light microscopy, electron microscopy, and confocal microscopy, provide detailed images of tissues at different scales. - Molecular Profiling: Techniques like single-cell RNA sequencing and proteomics allow for the analysis of gene and protein expression at the single-cell level, revealing the molecular heterogeneity within tissues.