What are the Strategies to Overcome These Challenges?
To address these challenges, various strategies have been developed: - Mucoadhesive Formulations: These help prolong the contact time of the drug with the mucosa, enhancing absorption. - Enzyme Inhibitors: Co-administering enzyme inhibitors can protect the drug from enzymatic degradation. - pH Modifiers: Formulations can include pH modifiers to stabilize the drug in the oral environment.
