Understanding the function and regulation of RYR1 has significant implications for both basic and clinical research. In basic research, studies on RYR1 contribute to our knowledge of muscle physiology and the mechanisms underlying excitation-contraction coupling. In clinical research, investigating RYR1 mutations and their effects can lead to improved diagnosis and treatment of muscle disorders, as well as the development of safer anesthetic protocols for individuals susceptible to malignant hyperthermia.
