What Are the Remedies for Cracked Paraffin Blocks?
If a paraffin block has already cracked, several steps can be taken to salvage the tissue sample:
Re-embedding: Carefully re-embed the tissue sample in a fresh paraffin block to restore structural integrity. Sectioning adjustments: Modify sectioning techniques, such as adjusting the microtome blade angle, to minimize the impact of cracks. Artifact identification: Be vigilant in identifying and documenting any artifacts introduced by cracks during microscopic examination.
