How Does Paraffin Block Cracking Affect Histological Analysis?
Paraffin block cracking can lead to several issues in histological analysis:
Difficulty in sectioning: Cracks can cause the tissue block to fragment during sectioning, resulting in poor-quality tissue sections. Artifact introduction: Cracks can introduce artifacts that may be mistaken for pathological changes, leading to misinterpretation. Compromised staining: Cracks can interfere with uniform staining, resulting in uneven or incomplete staining patterns.
