What are the Pathological Implications of Carbohydrate Chains?
Abnormal glycosylation of carbohydrate chains can lead to various diseases. For example, defects in glycosylation are involved in cancer progression and metastasis, as altered glycan structures can affect cell signaling and immune recognition. Congenital disorders of glycosylation (CDG) are a group of inherited conditions that result from defects in the glycosylation pathways, leading to multi-systemic symptoms.