identification of apoptotic cells

What Are the Molecular Markers of Apoptosis?

Molecular markers of apoptosis include:
- Caspase Activation: Caspases are proteases that execute apoptosis by cleaving specific substrates.
- Cleaved PARP: Poly (ADP-ribose) polymerase is cleaved by caspases during apoptosis.
- Bcl-2 Family Proteins: Regulate mitochondrial membrane permeability and apoptosis.
- Phosphatidylserine Exposure: Externalization of phosphatidylserine serves as an early marker of apoptosis.

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