The ovarian stroma is composed of several key components:
Stromal Cells: These are spindle-shaped cells that form the bulk of the stroma. They are responsible for producing extracellular matrix and contribute to the structural integrity of the ovary. Extracellular Matrix (ECM): This includes collagen fibers, glycoproteins, and proteoglycans that provide mechanical support and facilitate cell signaling. Blood Vessels: The stroma is richly vascularized, ensuring an adequate supply of nutrients and oxygen to the ovarian tissue. Immune Cells: Macrophages and other immune cells are present in the stroma, playing a role in tissue remodeling and immune surveillance.