serology:

What are the Limitations of Serology in Histology?

While serology offers valuable insights, it has limitations:
False Positives and Negatives: Serological tests can sometimes yield inaccurate results, influenced by cross-reactivity or technical errors.
Lack of Localization: Serology provides information about the presence of antibodies or antigens but does not indicate their precise location within tissues.
Temporal Information: Serological tests may not reflect the current disease state, as antibodies can persist long after the initial infection or exposure.

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